19-P001 Smed-evi/wntless is required for β-catenin-dependent and -independent processes during planarian regeneration
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منابع مشابه
19-P001 Smed-evi/wntless is required for β-catenin-dependent and -independent processes during planarian regeneration
19-P001 Smed-evi/wntless is required for b-catenin-dependent and independent processes during planarian regeneration Teresa Adell, Emili Saló, Michael Boutros, Kerstin Bartscherer 1 Department of Genetics and Institute of Biomedicine of the University of Barcelona (IBUB), Barcelona, Spain 2 German Cancer Research Center, Div. of Signaling and Functional Genomics, Heidelberg, Germany 3 Universit...
متن کامل19-P003 Proliferation and cell fates during regeneration of the adult zebrafish brain
19-P001 Smed-evi/wntless is required for b-catenin-dependent and independent processes during planarian regeneration Teresa Adell, Emili Saló, Michael Boutros, Kerstin Bartscherer 1 Department of Genetics and Institute of Biomedicine of the University of Barcelona (IBUB), Barcelona, Spain 2 German Cancer Research Center, Div. of Signaling and Functional Genomics, Heidelberg, Germany 3 Universit...
متن کاملEarly planarian brain regeneration is independent of blastema polarity mediated by the Wnt/β-catenin pathway.
Analysis of anteroposterior (AP) axis specification in regenerating planarian flatworms has shown that Wnt/β-catenin signaling is required for posterior specification and that the FGF-like receptor molecule nou-darake (ndk) may be involved in restricting brain regeneration to anterior regions. The relationship between re-establishment of AP identity and correct morphogenesis of the brain is, ho...
متن کاملLocalization of planarian β-CATENIN-1 reveals multiple roles during anterior-posterior regeneration and organogenesis.
The β-catenin-dependent Wnt pathway exerts multiple context-dependent roles in embryonic and adult tissues. In planarians, β-catenin-1 is thought to specify posterior identities through the generation of an anteroposterior gradient. However, the existence of such a gradient has not been directly demonstrated. Here, we use a specific polyclonal antibody to demonstrate that nuclear β-CATENIN-1 ex...
متن کاملThe planarian TCF/LEF factor Smed-tcf1 is required for the regeneration of dorsal-lateral neuronal subtypes.
The adult brain of the planarian Schmidtea mediterranea (a freshwater flatworm) is a dynamic structure with constant cell turnover as well as the ability to completely regenerate de novo. Despite this, function and pattern is achieved in a reproducible manner from individual to individual in terms of the correct spatial and temporal production of specific neuronal subtypes. Although several sig...
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ژورنال
عنوان ژورنال: Mechanisms of Development
سال: 2009
ISSN: 0925-4773
DOI: 10.1016/j.mod.2009.06.789